Read our briefer posts in which we share some of our clinical perspectives.
A comprehensive overview of current clinical implications and history of deprescribing in psychiatry.
A clinical overview covering ketamine’s mechanism of action, indications, treatment protocols, and safety considerations.
Brain Zaps: An Underappreciated Symptom of Antidepressant Discontinuation
by Papp A, Onton JA, 2018
Triggers and Characteristics of Brain Zaps According to the Findings of an Internet Questionnaire
by Papp A, Onton JA, 2022
More clinical perspectives to follow
Scholarly Articles on Ketamine
Acute Antidepressant Effects Of Intramuscular Versus Intravenous Ketamine
Indian Journal of Psychological Medicine – 2014
The ‘Ketamine And Me’ Project – A qualitative study of patients’ experience of ketamine treatment for depression
Journal of Affective Disorders Reports – 2021
Cognitive Behavior Therapy May Sustain Antidepressant Effects of Intravenous Ketamine in Treatment-Resistant Depression
Psychotherapy and Psychosomatics – 2017
GABA interneurons are the cellular trigger for ketamine’s rapid antidepressant actions
Journal of Clinical Investigation – 2020
Efficacy of Intravenous Ketamine for Treatment of Chronic Posttraumatic Stress Disorder
JAMA Psychiatry – 2014
Ketamine Assisted Psychotherapy (KAP): Patient Demographics, Clinical Data and Outcomes in Three Large Practices Administering Ketamine with Psychotherapy
Journal of Psychoactive Drugs – 2019
Ketamine Treatment For Depression: Opportunities For Clinical Innovation And Ethical Foresight
The Lancet Psychiatry – 2017
Replication of Ketamine’s Antidepressant Efficacy in Bipolar Depression: A Randomized Controlled Add-On Trial
Biological Psychiatry – 2012
Long-Term Maintenance With Intramuscular Ketamine for Treatment-Resistant Bipolar II Depression
American Journal of Psychiatry – 2012
Safety and efficacy of maintenance ketamine treatment in patients with treatment-refractory generalised anxiety and social anxiety disorders
Journal of Psychopharmacology – 2018
Side-effects Associated With Ketamine Use In Depression: A Systematic Review
The Lancet Psychiatry – 2018
Synaptic Potentiation Is Critical for Rapid Antidepressant Response to Ketamine
Biological Psychiatry – 2012
What Is The Mechanism Of Ketamine’s Rapid-onset Antidepressant Effect? A Concise Overview Of The Surprisingly Large Number Of Possibilities
Journal of Clinical Pharmacy and Therapeutics – 2017