
How Stress and Bipolar Disorder Interact: Causes, Course, and Treatment
All Posts, Diagnoses & Conditions, Psychotherapy, Science
Stress and bipolar disorder (BD) interact bidirectionally. Stress, particularly in early life, appears to have lasting effects and marks for early onset of BD, although the exact mechanism is poorly understood. The relationship of stress…

A New Oral Medication for Postpartum Depression
All Posts, Diagnoses & Conditions, Medications
The first oral pill approved by the US Food and Drug Administration (FDA) to treat postpartum depression, called Zurzuvae, developed by Sage Therapeutics, is now available by prescription. The medication, approved in August, is currently available…

Call 988!
All Posts, Diagnoses & Conditions
The “988 Lifeline” service was launched in July 2022, progressing from the narrow focus on suicide prevention as the “National Suicide Prevention Lifeline” to a wider attention of forms of acute distress (and also requiring a much…

Cannabis DUI
All Posts, Diagnoses & Conditions
The legalization of cannabis in certain regions has sparked a shift in the landscape of substance use among young people, with an emerging trend indicating that more individuals are driving under the influence of cannabis than alcohol. As…

A New PAM on the Block
All Posts, Diagnoses & Conditions, Science
Most of our readers know about antianxiety medications like Valium or Klonopin, and may know that their generic names are diazepam or clonazepam. The “pam” in these names stands for Positive Allosteric Modulator, and this fancy term means…

Supplements with Antianxiety Effects
All Posts, Diagnoses & Conditions, Herbs and Vitamins
Many people are interested in using herbs and vitamins, collectively called nutraceuticals, either alone or with therapy or medication to feel more in control of their treatment.
Nutraceuticals are supplements derived from food sources…

Cocaine and its Negative Side Effects
All Posts, Diagnoses & Conditions, Side Effects
As with other drugs, cocaine affects the nerve cells of the ventral segmental area, which extends into the nucleus accumbens, one of the reward centers of the brain. Cocaine acts as a reuptake inhibitor of dopamine, whose increased presence…

Brain, Behavior, and Drugs
All Posts, Diagnoses & Conditions, Science
I. The complex and adaptive brain
Brain architecture: gross anatomy, neurons
How the brain communicates
Adaptation and learning
II. How drugs hijack the brain
Pleasure and the reward center: the dopamine…

The Diagnosis of Bipolar II Disorder
All Posts, Diagnoses & Conditions, Science
Bipolar II Disorder is a mood disorder, characterized by shifting states between hypomania and depression. Diagnosing Bipolar II Disorder is particularly difficult, because those with this disorder often do not recognize their hypomanic…

What’s Your Caffeine IQ?
All Posts, Diagnoses & Conditions, Herbs and Vitamins
Caffeine Facts
For most people, moderate caffeine (200 – 300 mg, or about 2-3 cups of coffee a day) aren’t harmful. But heavy caffeine use (more than 500 mg) can cause insomnia, nervousness, restlessness, irritability, nausea…
