
Brain, Behavior, and Drugs*
All Posts, Medications, Science
I. The complex and adaptive brain
1. Brain architecture: gross anatomy, neurons
2. How the brain communicates
3. Adaptation and learning
II. How drugs hijack the brain
1. Pleasure and the…

Can a Pill Slow Aging? Geroscience, Health Span, and the Future of Anti-Aging Medicine
All Posts, Medications
Explore geroscience, health span vs. life span, biological age, and promising treatments like metformin, rapamycin, and senolytics in this blog entry.
Life Span vs. Health Span: Why the Distinction Matters
Scientists are starting…

The “Benzodiazepine Wars”: Risks, Benefits, and the Future of Anxiety Treatment
All Posts, Medications, Practice, Science
The benzodiazepine debate continues in psychiatry. Learn about the risks, benefits, and clinical guidance on benzodiazepine use for anxiety in this blog entry.
New Type of Media Coverage: Moving Beyond Fear and Stigma
The debate…

Lithium and Alzheimer’s Disease: New Research Links Low Brain Lithium to Memory Loss
All Posts, Diagnoses & Conditions, Medications, Science
New research has identified a surprising connection between lithium and Alzheimer’s disease, with potentially far-reaching implications for both early detection and disease-modifying therapy.
Lithium of a Different Color: A Surprising…

Does Naltrexone Block Ketamine’s Antidepressant Effect? The Opioid Receptor Problem in Ketamine Therapy
All Posts, Ketamine, Medications, Science
Are Ketamine’s Opiate Receptor Effects Necessary for Its Antidepressant Effect?
The question of whether ketamine’s antidepressant action depends on opioid receptor activity has significant implications for clinical practice — particularly…

The Resurgence of Psychedelic Psychiatry: An Exciting Yet Cautious Advance
All Posts, Diagnoses & Conditions, Ketamine, Medications
Read about the potential of psychedelics like MDMA and ketamine in treating psychiatric conditions, the advancements in research, and our commitment to safety in exploring these powerful therapies.
Introduction
Psychedelic…

Advancing Treatment Approaches for Treatment-Resistant Depression
All Posts, Diagnoses & Conditions, Ketamine, Medications
If multiple antidepressants haven't worked for you, you're not alone and you're not out of options.
Why Antidepressants Fail: Lessons from the STAR*D Study
Treatment-resistant depression (TRD) is a complex challenge in mental health,…

A New Oral Medication for Postpartum Depression
All Posts, Diagnoses & Conditions, Medications
The first oral pill approved by the US Food and Drug Administration (FDA) to treat postpartum depression, called Zurzuvae, developed by Sage Therapeutics, is now available by prescription. The medication, approved in August, is currently available…

Understanding Methylfolate: Genetic Connection and Clinical Insights
All Posts, Herbs and Vitamins, Medications, Science
In the ever-evolving landscape of mental health treatments, let's shine the spotlight on methylfolate, a form of folate (or folic acid, also known as vitamin B9), in the fight against depression.
Folate, a vital nutrient for neurotransmitter…

The “Pipeline”
All Posts, Ketamine, Medications, Science
There are several exciting developments in the field of antidepressants, with various drugs currently in the pipeline. These new treatments aim to provide better efficacy and fewer side effects compared to existing antidepressants. Here are…
