Brain, Behavior, and Drugs*

Brain, Behavior, and Drugs*

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I. The complex and adaptive brain 1. Brain architecture: gross anatomy, neurons 2. How the brain communicates 3. Adaptation and learning II. How drugs hijack the brain 1. Pleasure and the…
Can a Pill Slow Aging? Geroscience, Health Span, and the Future of Anti-Aging Medicine

Can a Pill Slow Aging? Geroscience, Health Span, and the Future of Anti-Aging Medicine

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Explore geroscience, health span vs. life span, biological age, and promising treatments like metformin, rapamycin, and senolytics in this blog entry. Life Span vs. Health Span: Why the Distinction Matters Scientists are starting…
The "Benzodiazepine Wars": Risks, Benefits, and the Future of Anxiety Treatment

The “Benzodiazepine Wars”: Risks, Benefits, and the Future of Anxiety Treatment

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The benzodiazepine debate continues in psychiatry. Learn about the risks, benefits, and clinical guidance on benzodiazepine use for anxiety in this blog entry. New Type of Media Coverage: Moving Beyond Fear and Stigma The debate…
Lithium and Alzheimer’s Disease: New Research Links Low Brain Lithium to Memory Loss

Lithium and Alzheimer’s Disease: New Research Links Low Brain Lithium to Memory Loss

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New research has identified a surprising connection between lithium and Alzheimer’s disease, with potentially far-reaching implications for both early detection and disease-modifying therapy. Lithium of a Different Color: A Surprising…
Does Naltrexone Block Ketamine’s Antidepressant Effect? The Opioid Receptor Problem in Ketamine Therapy

Does Naltrexone Block Ketamine’s Antidepressant Effect? The Opioid Receptor Problem in Ketamine Therapy

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Are Ketamine’s Opiate Receptor Effects Necessary for Its Antidepressant Effect? The question of whether ketamine’s antidepressant action depends on opioid receptor activity has significant implications for clinical practice — particularly…
The Resurgence of Psychedelic Psychiatry: An Exciting Yet Cautious Advance

The Resurgence of Psychedelic Psychiatry: An Exciting Yet Cautious Advance

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  Read about the potential of psychedelics like MDMA and ketamine in treating psychiatric conditions, the advancements in research, and our commitment to safety in exploring these powerful therapies. Introduction Psychedelic…
Advancing Treatment Approaches for Treatment-Resistant Depression

Advancing Treatment Approaches for Treatment-Resistant Depression

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If multiple antidepressants haven't worked for you, you're not alone and you're not out of options. Why Antidepressants Fail: Lessons from the STAR*D Study Treatment-resistant depression (TRD) is a complex challenge in mental health,…
A New Oral Medication for Postpartum Depression

A New Oral Medication for Postpartum Depression

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The first oral pill approved by the US Food and Drug Administration (FDA) to treat postpartum depression, called Zurzuvae, developed by Sage Therapeutics, is now available by prescription. The medication, approved in August, is currently available…
Understanding Methylfolate: Genetic Connection and Clinical Insights

Understanding Methylfolate: Genetic Connection and Clinical Insights

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In the ever-evolving landscape of mental health treatments, let's shine the spotlight on methylfolate, a form of folate (or folic acid, also known as vitamin B9), in the fight against depression.  Folate, a vital nutrient for neurotransmitter…
The "Pipeline"

The “Pipeline”

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There are several exciting developments in the field of antidepressants, with various drugs currently in the pipeline. These new treatments aim to provide better efficacy and fewer side effects compared to existing antidepressants. Here are…