
Ketamine for Chronic Pain? Evidence Still Missing
All Posts, Ketamine, Science
In a landscape where ketamine clinics are rapidly proliferating, evidence-based clinical decision-making matters even more.
A new recently published large review study by Ferraro et al. in the Cochrane database casts serious doubt on…

Navigating Complex Ketamine Treatment: A Case Study on Ketamine Therapy and Bipolar Diagnosis in Psychiatric Practice
All Posts, Diagnoses & Conditions, Ketamine, Practice
A clinical case study on how integrated ketamine therapy and psychiatric care at Point Loma Clinic enabled early detection of a shift from depression to bipolar disorder.
Patient Background: Treatment-Resistant Depression and a History…

Ketamine and Postpartum Depression: A Promising New Treatment Option
All Posts, Diagnoses & Conditions, Ketamine, Science
A new study published in The British Medical Journal looked into whether giving a single low dose of ketamine (in the form of esketamine) right after childbirth could help reduce postpartum depression in mothers who were depressed during pregnancy.
How…

Does Naltrexone Block Ketamine’s Antidepressant Effect? The Opioid Receptor Problem in Ketamine Therapy
All Posts, Ketamine, Medications, Science
Are Ketamine’s Opiate Receptor Effects Necessary for Its Antidepressant Effect?
The question of whether ketamine’s antidepressant action depends on opioid receptor activity has significant implications for clinical practice — particularly…

Predicting Ketamine Treatment Outcomes: Key Findings and Implications
All Posts, Ketamine, Science
Understanding which patients are most likely to respond to ketamine therapy is one of the most important task in the treatment of depression.
Introduction
The study "Predicting non-response to ketamine for depression: An exploratory…

The Comparative Effectiveness of Ketamine vs. Traditional Antidepressants: Personal Stories
All Posts, Diagnoses & Conditions, Ketamine, Science
Introduction: What the Clinical Research Shows
Recent clinical studies have explored the comparative effectiveness of ketamine and traditional antidepressants in treating depression. The quantitative differences are striking:
Remission…

The Resurgence of Psychedelic Psychiatry: An Exciting Yet Cautious Advance
All Posts, Diagnoses & Conditions, Ketamine, Medications
Read about the potential of psychedelics like MDMA and ketamine in treating psychiatric conditions, the advancements in research, and our commitment to safety in exploring these powerful therapies.
Introduction
Psychedelic…

Advancing Treatment Approaches for Treatment-Resistant Depression
All Posts, Diagnoses & Conditions, Ketamine, Medications
If multiple antidepressants haven't worked for you, you're not alone and you're not out of options.
Why Antidepressants Fail: Lessons from the STAR*D Study
Treatment-resistant depression (TRD) is a complex challenge in mental health,…

OCD and Depression: Why OCD Is Often Misdiagnosed
All Posts, Ketamine, Psychotherapy
Many people living with OCD spend years — even decades — before receiving a diagnosis of OCD, despite seeing multiple treatment providers. This post explains why this happens, what the research shows, and what an accurate diagnosis and…

Unlocking the Brain: How the Lateral Habenula Influences Depression and Ketamine Therapy
All Posts, Ketamine, Science
The lateral habenula (LHb) stands out as a critical structure in understanding depression. This blog explores the LHb's role in the intricate landscape of neuroscience, its connection to depressive symptoms, and how ketamine therapy offers…
