Ketamine for Chronic Pain? Evidence Still Missing

Ketamine for Chronic Pain? Evidence Still Missing

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In a landscape where ketamine clinics are rapidly proliferating, evidence-based clinical decision-making matters even more. A new recently published large review study by Ferraro et al. in the Cochrane database casts serious doubt on…
Navigating Complex Ketamine Treatment: A Case Study on Ketamine Therapy and Bipolar Diagnosis in Psychiatric Practice

Navigating Complex Ketamine Treatment: A Case Study on Ketamine Therapy and Bipolar Diagnosis in Psychiatric Practice

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A clinical case study on how integrated ketamine therapy and psychiatric care at Point Loma Clinic enabled early detection of a shift from depression to bipolar disorder. Patient Background: Treatment-Resistant Depression and a History…
Ketamine and Postpartum Depression: A Promising New Treatment Option

Ketamine and Postpartum Depression: A Promising New Treatment Option

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A new study published in The British Medical Journal looked into whether giving a single low dose of ketamine (in the form of esketamine) right after childbirth could help reduce postpartum depression in mothers who were depressed during pregnancy. How…
Does Naltrexone Block Ketamine’s Antidepressant Effect? The Opioid Receptor Problem in Ketamine Therapy

Does Naltrexone Block Ketamine’s Antidepressant Effect? The Opioid Receptor Problem in Ketamine Therapy

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Are Ketamine’s Opiate Receptor Effects Necessary for Its Antidepressant Effect? The question of whether ketamine’s antidepressant action depends on opioid receptor activity has significant implications for clinical practice — particularly…
Study Background: Ketamine Treatment at the VA San Diego Medical Center

Predicting Ketamine Treatment Outcomes: Key Findings and Implications

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Understanding which patients are most likely to respond to ketamine therapy is one of the most important task in the treatment of depression. Introduction The study "Predicting non-response to ketamine for depression: An exploratory…
The Comparative Effectiveness of Ketamine vs. Traditional Antidepressants: Personal Stories

The Comparative Effectiveness of Ketamine vs. Traditional Antidepressants: Personal Stories

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Introduction: What the Clinical Research Shows Recent clinical studies have explored the comparative effectiveness of ketamine and traditional antidepressants in treating depression. The quantitative differences are striking: Remission…
The Resurgence of Psychedelic Psychiatry: An Exciting Yet Cautious Advance

The Resurgence of Psychedelic Psychiatry: An Exciting Yet Cautious Advance

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  Read about the potential of psychedelics like MDMA and ketamine in treating psychiatric conditions, the advancements in research, and our commitment to safety in exploring these powerful therapies. Introduction Psychedelic…
Advancing Treatment Approaches for Treatment-Resistant Depression

Advancing Treatment Approaches for Treatment-Resistant Depression

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If multiple antidepressants haven't worked for you, you're not alone and you're not out of options. Why Antidepressants Fail: Lessons from the STAR*D Study Treatment-resistant depression (TRD) is a complex challenge in mental health,…
OCD and Depression: Why OCD Is Often Misdiagnosed

OCD and Depression: Why OCD Is Often Misdiagnosed

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Many people living with OCD spend years — even decades — before receiving a diagnosis of OCD, despite seeing multiple treatment providers. This post explains why this happens, what the research shows, and what an accurate diagnosis and…
Unlocking the Brain: How the Lateral Habenula Influences Depression and Ketamine Therapy

Unlocking the Brain: How the Lateral Habenula Influences Depression and Ketamine Therapy

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The lateral habenula (LHb) stands out as a critical structure in understanding depression. This blog explores the LHb's role in the intricate landscape of neuroscience, its connection to depressive symptoms, and how ketamine therapy offers…