Ketamine and the Future of Mental Health: Insights from the 2024 Oxford International Conference

Ketamine and the Future of Mental Health: Insights from the 2024 Oxford International Conference

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Introduction The Oxford Ketamine International Conference in March 2024 brought together leading experts and researchers from around the world to explore the basic science and therapeutic use of ketamine.  Oxford, with its esteemed university…
The Risks of At-Home Ketamine: A Cautionary Perspective

The Risks of At-Home Ketamine: A Cautionary Perspective

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Introduction Ketamine, an NMDA receptor antagonist, has shown promise in the treatment of various psychiatric disorders, including depression and PTSD. Its rapid-acting therapeutic effects have made it an appealing option in clinical…
Exploring Ketamine Therapy Risks in Light of Matthew Perry's Untimely Passing

Exploring Ketamine Therapy Risks in Light of Matthew Perry’s Untimely Passing

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Matthew Perry, celebrated for his iconic role on "Friends," tragically passed away on October 28, 2023, after being found unresponsive at the heated end of his swimming pool. His live-in personal assistant discovered him upon returning from…
The "Pipeline"

The “Pipeline”

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There are several exciting developments in the field of antidepressants, with various drugs currently in the pipeline. These new treatments aim to provide better efficacy and fewer side effects compared to existing antidepressants. Here are…
Cough Medicine for Depression?

Cough Medicine for Depression?

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Yes, cough medicine! This blog entry touches upon the same issue that was detailed in the “What’s In a Name...” blog entry of November 2020. Medications are "born” with a certain designation, which then follows them throughout…
Ketamine Dreams 2: Travels through Memories of Land and People

Ketamine Dreams 2: Travels through Memories of Land and People

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It is immensely gratifying for us to see the robust response to ketamine in some patients, especially since many of them had struggled with depression for years, trying one medication after another, with only partial success at best, while…
Ketamine Dreams 1: Visions of Sand and Stars in Patient Narratives

Ketamine Dreams 1: Visions of Sand and Stars in Patient Narratives

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One type of feedback we collect from our ketamine patients is a narrative description of their experiences during the “trip”. It is hard to remember, let alone put in words, psychedelic experiences and many of our patients leave empty…
Psychotherapy Coordinated with Ketamine Treatment

Psychotherapy Coordinated with Ketamine Treatment

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How Ketamine Opens the Door to Therapeutic Breakthroughs One of the most compelling and underutilized applications of ketamine treatment is its capacity to augment psychotherapy — not just as a stand-alone antidepressant, but as a tool…
When Ketamine Is No Longer Indicated, or a Disappointed Patient

When Ketamine Is No Longer Indicated, or a Disappointed Patient

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A Case Study in Depression, Hypomania, and Bipolar Diagnosis Joe (a fictionalized name; real patient, case shared with permission) was in his mid-fifties, an accomplished attorney who had suffered from recurrent depression since his early…
When the Ketamine Trip is a Dud

When the Ketamine Trip is a Dud

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Ketamine Works Even When You Feel Nothing Patients who receive ketamine for depression, PTSD or other indications, experience distortions of time and space, and a loss of sense of self, during the peak blood levels of ketamine. These…