Don't Throw Out the Serotonin Theory Just Yet!

Don’t Throw Out the Serotonin Theory Just Yet!

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The serotonin theory of depression has been around for a good 60 years and is often used as justification for the use of antidepressants, specifically selective serotonin re-uptake inhibitors (SSRIs). Understandably, a review published…
A New PAM on the Block

A New PAM on the Block

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Most of our readers know about antianxiety medications like Valium or Klonopin, and may know that their generic names are diazepam or clonazepam. The “pam” in these names stands for Positive Allosteric Modulator, and this fancy term means…
The "Pipeline"

The “Pipeline”

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There are several exciting developments in the field of antidepressants, with various drugs currently in the pipeline. These new treatments aim to provide better efficacy and fewer side effects compared to existing antidepressants. Here are…
More on Brain Zaps

More on Brain Zaps

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The article mentioned in our January 2020 blog entry was followed by a more comprehensive work which was published in 2022 (Triggers and Characteristics of Brain Zaps According to the Findings of an Internet Questionnaire.) The study…
Supplements with Antianxiety Effects

Supplements with Antianxiety Effects

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Many people are interested in using herbs and vitamins, collectively called nutraceuticals, either alone or with therapy or medication to feel more in control of their treatment. Nutraceuticals are supplements derived from food sources…
Cough Medicine for Depression?

Cough Medicine for Depression?

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Yes, cough medicine! This blog entry touches upon the same issue that was detailed in the “What’s In a Name...” blog entry of November 2020. Medications are "born” with a certain designation, which then follows them throughout…
Heart Rate Variability Biofeedback

Heart Rate Variability Biofeedback

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Biofeedback is a commonly used method to teach individuals voluntary control of physiological functions.   Specific biofeedback techniques include electromyography (measures muscle tension), galvanized skin response (measures sweat response),…
Cocaine and its Negative Side Effects

Cocaine and its Negative Side Effects

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As with other drugs, cocaine affects the nerve cells of the ventral segmental area, which extends into the nucleus accumbens, one of the reward centers of the brain.  Cocaine acts as a reuptake inhibitor of dopamine, whose increased presence…
Brain, Behavior, and Drugs

Brain, Behavior, and Drugs

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I.  The complex and adaptive brain Brain architecture:  gross anatomy, neurons How the brain communicates Adaptation and learning II.  How drugs hijack the brain Pleasure and the reward center:  the dopamine…
The Diagnosis of Bipolar II Disorder

The Diagnosis of Bipolar II Disorder

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Bipolar II Disorder  is a mood disorder, characterized by shifting states between hypomania and depression. Diagnosing Bipolar II Disorder is particularly difficult, because those with this disorder often do not recognize their hypomanic…